ProGP202 (TMBP (Trehalose/maltose binding protein)

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ProGP ID ProGP202 (TMBP (Trehalose/maltose binding protein)
Validation Status Uncharacterized
Organism Information
Organism NameThermococcus litoralis DSM 5473
Domain Archaea
Classification Phylum : Euryarchaeota
Class : Thermococci
Orders : Thermococcales
Family : Thermococcaceae
Genus : Thermococcus
Species : litoralis
Strain : DSM 5473
Taxonomic ID (NCBI) 2265
Genome Information
GenBank AF012836
EMBL AF012836
Gene Information
Gene NamemalE
Protein Information
Protein NameTMBP (Trehalose/maltose binding protein)
UniProtKB/SwissProt ID Q7LYW7
EMBL-CDSAAC38136.1
UniProtKB Sequence >tr|Q7LYW7|Q7LYW7_THELI Trehalose/maltose binding protein OS=Thermococcus litoralis GN=malE PE=4 SV=1 MNVKKVLLGLFLVGVLGIAVVASGCIGGQQTSTVTSTPTETSLQGKIVFAVGGAPNEIEY WKGVIAEFEKKYPGVTVELKRQATDTEQRRLDLVNALRGKSSDPDVFLMDVAWLGQFIAS GWLEPLDDYVQKDNYDLSVFFQSVINLADKQGGKLYALPVYIDAGLLYYRKDLLEKYGYS KPPETWQELVEMAQKIQSGERETNPNFWGFVWQGKQYEGLVCDFVEYVYSNGGSLGEFKD GKWVPTLNKPENVEALQFMVDLIHKYKISPPNTYTEMTEEPVRLMFQQGNAAFERNWPYA WGLHNADDSPVKGKVGVAPLPHFPGHKSAATLGGWHIGISKYSDNKALAWEFVKFVESYS VQKGFAMNLGWNPGRVDVYDDPAVVSKSPHLKELRAVFENAVPRPIVPYYPQLSEIIQKY VNSALAGKISPQEALDKAQKEAEELVKQYS
Sequence length 450 AA
Subcellular LocationMembrane
Function This soluble protein is involved in ABC transport of trehalose and maltose. It has got an exceptionally high substrate-binding affinity and transports the substrates at 85°C.
Glycosylation Status
Technique(s) used for Glycosylation DetectionPAS-staining and ConA-Sepharose affinity chromatography.
Literature
Year of Identification2001
Year of Identification Month Wise2001.7
ReferenceGreller, G., Riek, R. and Boos, W., 2001. Purification and characterization of the heterologously expressed trehalose/maltose ABC transporter complex of the hyperthermophilic archaeon Thermococcus litoralis. European Journal of Biochemistry, 268(14), pp.4011-4018.
Corresponding Author Winfried Boos
ContactDepartment of Biology, University of Konstanz, Germany